Ryan Inniss, Terell Thomas, Albie Morgan and Tyreece Campbell also start in Lancashire, while Jes Rak-Sakyi, who came off injured on Saturday, is fit enough for the bench.
If the Addicks line-up in a 4-3-3 formation it will mean Sean Clare, Inniss, Michael Hector and Thomas will make up a back four in front of goalkeeper Ashley Maynard-Brewer.
Lucas Ness misses out having picked up a patella tendon injury at the weekend and will see a specialist next week.
Steven Sessegnon misses out with knee swelling, meaning there is a place on the bench for the returning Mandela Egbo
Fraser and Morgan join skipper George Dobson in a midfield three behind attacking trio Campbell, Miles Leaburn and Corey Blackett-Taylor.
Rak-Sakyi and Egbo are joined on the bench by Joe Wollacott, Aaron Henry, Jack Payne, Macauley Bonne and Dan Kanu.
Charlton: Maynard-Brewer; Clare, Inniss, Hector, Thomas; Morgan, Dobson (c), Fraser; Campbell, Leaburn, Blackett-Taylor
Substitutes: Wollacott, Egbo, Henry, Payne, Rak-Sakyi, Bonne, Kanu
Comments
"Tonight it's do or die!"
I think I just split my jeans.
Bold if so to play Thomas at LB.
It's certainly not Penney who once again shows that going cheap = a waste of money, not a bargain!
Top goal scorer on the bench.
And would be madness to play CBT up top
Reverse psychology - we'll win this one.
Can't believe people aren't really up for this one!